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Table 2 Clinical factors associated with pN+ in patients with early or advanced gastric cancer

From: Clinical significance of neutrophil-to-lymphocyte ratio as a predictor of lymph node metastasis in gastric cancer

A: Early gastric cancer (cT1) (n = 277)

Variables

Pathological lymph node metastasis (pN+) (n = 30)

Univariate

Multivariate

OR

95% CI

p value

OR

95% CI

p value

Sex

  

0.704

   

 Male

1

     

 Female

1.163

0.524–2.503

    

Age

  

0.629

   

  < 65

1.205

0.561–2.590

    

  ≥ 65

1

     

Tumor location

  

0.353

   

 Upper

1.464

0.644–3.189

    

 Middle/Lower

1

     

cN

  

0.002

   

 N0

1

     

 N+

9.680

2.537–37.07

    

NLR

  

0.069

   

 Low (< 1.6)

1

     

 High (≥1.6)

2.253

0.942–6.266

    

B: Advanced gastric cancer (cT2-T4) (n = 152)

Variables

Pathological lymph node metastasis (pN+) (n = 86)

Univariate

Multivariate

OR

95% CI

p value

OR

95% CI

p value

Sex

  

0.424

   

 Male

1

     

 Female

1.325

0.666–2.679

    

Age

  

0.496

   

  < 65

1

     

  ≥ 65

1.263

0.644–2.476

    

Tumor location

  

0.968

   

 Upper

1

     

 Middle/Lower

1.014

0.518–1.975

    

cN

  

0.014

  

0.011

 N0

1

  

1

  

 N+

2.300

1.183–4.573

 

2.426

1.221–4.958

 

NLR

  

0.005

  

0.004

 Low (< 1.6)

1

  

1

  

 High (≥1.6)

3.004

1.399–6.687

 

3.171

1.448–7.235

 
  1. NLR neutrophil-to-lymphocyte ratio