Radical radiotherapy in patients with cervix uteri carcinoma: experience of Ondokuz Mayis University

BMC Cancer

Table 2 Three-years survival rates of univariate analysis according to the prognostic factors

	LRFFS		DMFS		PFS		OS
	%	P	%	P	%	P	%	P
FIGO stage		0.003		0.26		0.01		0.03
≤ IIA	100		100		100		100
IIB	95.0		75.9		75.9		88.1
III	71.3		65.0		46.0		52.6
IV	50.0		100		50.0		100
Node metastasis		0.42		0.15		0.14		0.09
Negative	95.2		83.3		79.2		91.7
Positive	79.2		69.7		57.8		65.9
Parametrial invasion		0.95		0.42		0.60		0.84
Positive	92.1		71.7		68.2		73.5
Negative	75.0		90.9		68.1		88.9
Tumor size		0.94		0.19		0.08		0.11
≤ 5 cm	90.0		80.6		71.7		79.2
> 5 cm	84.1		68.0		61.0		56.8
Initial tumor volume		0.39		0.76		0.32		0.53
< 65 cm³	86.5		75.7		67.3		62.4
≥ 65 cm³	88.4		77.3		67.7		63.7
HR-CTV		0.18		0.39		0.06		0.12
≤ 30 cm³	95.2		81.7		81.7		84.6
> 30 cm³	75.9		68.8		49.6		70.0
Chemothrapy		0.34		0.77		0.64		0.82
≤ 4 course	74.3		71.1		49.5		87.5
≥ 5 course	94.4		78.2		76.2		73.9
D90 (EQD2)		0.01		0.95		0.23		0.17
≤ 90 Gy	65.0		67.7		41.4		72.9
> 90 Gy	100		78.6		78.6		80.2

LRFFS loco-regional failure-free survival, PFS progression-free survival, DMSF distant metastasis-free survival, OS overall survival, FIGO Fédération Internationale de Gynécologie et d’Obstétrique, HR-CTV High risk clinical target volume

ISSN: 1471-2407