The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo

Table 2 Characteristics of mice and tumors within the intrasplenic xenotransplantation model

Experiment	Characteristics	Control	HEYL	p-value
M1	Number of mice	6	6
	Tumor weight [g] median (range)	1.68 (0.2–2.3)	2.45 (2.1–3.0)	0.022
	Time to tumor growth [d] median (range)	42 (32–44)	36.5 (27–44)	0.447
NM1	Number of mice (+death)	5 (+ 1)	6
	Tumor weight [g] median (range)	4.97 (0.4–5.8)	2.65 (1.3–4.1)	0.222
	Time to tumor growth [d] median (range)	50 (50–54)	50 (35–54)	0.174

ISSN: 1471-2407