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Table 7 Univariate analysis of Overall Survival in ER+ patients

From: Metabolic consequences of perioperative oral carbohydrates in breast cancer patients — an explorative study

Variable

Events /At risk

% survival

P

HR

95% CI

Carbo/Faste

 Faste

1/29

97

   

 Carbohydrate

4/21

81

0.068

6.02

0.675–53.8

S-Pyruvata

 < 12.5

1/39

97

   

 ≥ 12.5

4/10

60

<0.0001

19.2

2.14–172

S-Lactatea

 < 56.9

2/40

95

   

 ≥ 56.9

3/9

67

0.009

7.58

1.26–45.4

S-Preop Insulin

 < 18.3 I.U.

1/29

97

   

 ≥ 18.3 I.U.

4/21

81

0.068

6.016

0.672–53.9

S-Preoperative C-peptide

 < 1.22 nM

1/29

97

   

 ≥1.22 nM

4/21

81

0.068

6.02

0.672–53.9

Tissue Glutathione

 ≤1.0855

1/10

90

   

 >1.0855

3/8

63

0.140

4.72

0.488–45.7

Tumor size

 T1

1/40

98

   

 T2

4/10

60

< 0.0001

19.2

2.20 –176

Nodal status

 N0

2/33

94

   

 N+

3/17

82

0.205

3.01

0.502–18.0

Grade

 1

0/11

100

   

 2+3

5/39

87

0.222

30.2

0.004–223736

MAIa

 <10

3/39

92

   

 ≥10

2/10

80

0.235

2.83

0.471–16.9

Ki67a

 <30%

2/37

95

   

 ≥30%

3/12

75

0.049

5.040

0.842–30.2

PPH3

 <13

3/35

91

   

 ≥13

2/15

87

0.641

1.53

0.255–9.13

  1. aMissing information on one patient in the ER+ group leading to n=49 patients analyzed for this variable