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Table 6 Univariate analysis of Breast Cancer Specific Survival in ER+ patients

From: Metabolic consequences of perioperative oral carbohydrates in breast cancer patients — an explorative study

Variable

Events /

At risk

% Survival

P

HR

95% CI

Fasting /Carbohydrate

 Fasting

0/29

100

   

 Carbohydrate

4/21

81

0.015

Inf.

 

S-Pyruvate

 < 12.5

0/40

100

   

 ≥ 12.5

4/10

60

<0. 0001

Inf.

 

S-Lactatea

 < 56.9

1/40

98

   

 ≥ 56.9

3/9

67

0.002

14.8

1.53-142

S-Preoperative Insulin

 < 18.3 I.U.

0/29

100

   

 ≥ 18.3 I.U.

4/21

81

0.015

Inf.

 

S-Preoperative C-peptide

 < 1.22 nM

0/29

100

   

 ≥1.22 nM

4/21

81

0.015

103

0.025-429676

Tumor

Glutathione

 < 1.09

0/10

100

   

 ≥ 1.09

3/8

63

0.038

Inf.

 

Tumor size

 T1

0/40

100

   

 T2

4/10

60

<0.0001

Inf.

 

Nodal status

 N0

1/33

97

   

 N+

3/17

82

0.080

5.92

0.615 – 56.9

Grade

 1

0/11

100

   

 2+3

4/39

90

0.277

30.1

Inf.

MAIa

 <10

2/39

95

   

 ≥10

2/10

80

0.124

4.12

0.580- 29.3

Ki67a

 <30%

1/37

97

   

 ≥30%

3/12

75

0.014

9.91

1.03-95.3

PPH3

 <13

2/35

94

   

 ≥13

2/15

87

0.399

2.27

0.320 – 16.1

  1. aMissing information on one patient in the ER+ group leading to n=49 patients analyzed for this variable