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Table 5 Univariate analysis of Relapse Free Survival in ER+ patients

From: Metabolic consequences of perioperative oral carbohydrates in breast cancer patients — an explorative study

Variable

Events / At risk

% Survival

P

HR

95% CI

Fasting / Carbohydrate

 Fasting

1/29

97

   

 Carbohydrate

6/21

71

0.012

9.34

1.12 –77.7

S-Pyruvatea

 < 12.5

2/39

95

   

 ≥ 12.5

5/10

50

<0.0001

13.59

2.61– 70.6

S-Lactatea

 < 56.9

3/40

93

   

 ≥ 56.9

4/9

56

0.002

7.47

1.66 – 33.6

S-Preoperative Insulin

 < 18.3 I.U.

1/29

97

   

 ≥ 18.3 I.U.

6/21

71

0.012

9.34

1.12 – 77.7

S-Preoperative C-peptide

 < 1.22 nM

1/29

97

   

 ≥1.22 nM

6/21

71

0.011

9.51

1.14-79.0

Tumor

Glutathione

 < 1.09

0/10

100

   

 ≥ 1.09

3/8

63

0.038

Inf.

 

Tumor size

 T1

3/40

93

   

 T2

4/10

60

0.003

7.09

1.57-31.9

Nodal status

 N0

3/33

91

   

 N+

4/17

73

0.160

2.80

0.625-12.6

Grade

 1

0/11

100

   

 2+3

7/39

82

0.136

31.1

0.019 – 50547

MAIa

 <10

4/39

90

   

 ≥10

3/10

70

0.092

3.38

0.751–15.2

Ki67a

 <30%

3/37

92

   

 ≥30%

4/12

67

0.023

4.84

1.08 – 21.8

PPH3

 <13

3/35

91

   

 ≥13

4/15

73

0.116

3.13

0.699-14.0

  1. aMissing information on one patient in the ER+ group leading to n=49 patients analyzed for this variable