Table 12 Results from Quantitative Metabolite Set Enrichment Analysis
Metabolic pathway | Total Cmpd | Hits | Statistic Q (Expected 1.613) | Raw p | FDR |
Amino Sugar Metabolism | 33 | 3 | 24.50 | 0.000 | 0.000 |
Propanoate Metabolism | 42 | 1 | 44.09 | 0.000 | 0.000 |
Valine, Leucine and Isoleucine Degradation | 60 | 4 | 31.60 | 0.000 | 0.000 |
Pyruvate Metabolism | 48 | 3 | 28.66 | 0.000 | 0.000 |
Phenylalanine and Tyrosine Metabolism | 28 | 2 | 31.54 | 0.000 | 0.000 |
Fatty Acid Biosynthesis | 35 | 3 | 25.58 | 0.000 | 0.000 |
Aspartate Metabolism | 35 | 3 | 16.23 | 0.000 | 0.000 |
Ethanol Degradation | 19 | 1 | 33.64 | 0.000 | 0.000 |
Tyrosine Metabolism | 72 | 1 | 32.22 | 0.000 | 0.000 |
Butyrate Metabolism | 19 | 1 | 32.22 | 0.000 | 0.000 |
Lysine Degradation | 30 | 1 | 31.52 | 0.000 | 0.000 |
Biotin Metabolism | 8 | 1 | 31.52 | 0.000 | 0.000 |
Carnitine Synthesis | 22 | 1 | 31.52 | 0.000 | 0.000 |
Ammonia Recycling | 32 | 3 | 14.09 | 0.000 | 0.000 |
Warburg Effect | 58 | 5 | 13.16 | 0.000 | 0.000 |
Cysteine Metabolism | 26 | 1 | 27.23 | 0.000 | 0.000 |
Pyruvaldehyde Degradation | 10 | 1 | 27.23 | 0.000 | 0.000 |
Urea Cycle | 29 | 3 | 13.38 | 0.000 | 0.000 |
Glutamate Metabolism | 49 | 3 | 13.38 | 0.000 | 0.000 |
Gluconeogenesis | 35 | 3 | 17.45 | 0.000 | 0.000 |
Ketone Body Metabolism | 13 | 2 | 17.24 | 0.000 | 0.000 |
Glycolysis | 25 | 2 | 13.61 | 0.000 | 0.000 |
Citric Acid Cycle | 32 | 2 | 14.00 | 0.000 | 0.001 |
Glycine and Serine Metabolism | 59 | 5 | 8.26 | 0.000 | 0.001 |
Alanine Metabolism | 17 | 2 | 13.75 | 0.000 | 0.001 |
Transfer of Acetyl Groups into Mitochondria | 22 | 3 | 9.34 | 0.001 | 0.001 |
Glucose-Alanine Cycle | 13 | 3 | 9.17 | 0.001 | 0.002 |
Pyrimidine Metabolism | 59 | 1 | 12.64 | 0.005 | 0.008 |
Nicotinate and Nicotinamide Metabolism | 37 | 1 | 12.64 | 0.005 | 0.008 |
Purine Metabolism | 74 | 1 | 12.64 | 0.005 | 0.008 |
Phenylacetate Metabolism | 9 | 1 | 12.64 | 0.005 | 0.008 |
Threonine and 2-Oxobutanoate Degradation | 20 | 1 | 7.42 | 0.035 | 0.048 |
Methionine Metabolism | 43 | 1 | 6.38 | 0.052 | 0.065 |
Betaine Metabolism | 21 | 1 | 6.38 | 0.052 | 0.065 |
Spermidine and Spermine Biosynthesis | 18 | 1 | 6.38 | 0.052 | 0.065 |
Glycerolipid Metabolism | 25 | 1 | 5.74 | 0.065 | 0.080 |
Galactose Metabolism | 38 | 2 | 2.87 | 0.184 | 0.219 |
Arginine and Proline Metabolism | 53 | 2 | 0.94 | 0.575 | 0.665 |
Glutathione Metabolism | 21 | 1 | 0.27 | 0.692 | 0.743 |
Selenoamino Acid Metabolism | 28 | 1 | 0.27 | 0.692 | 0.743 |
Tryptophan Metabolism | 60 | 1 | 0.27 | 0.692 | 0.743 |
Sphingolipid Metabolism | 40 | 1 | 0.00 | 0.969 | 0.969 |
Lactose Synthesis | 20 | 1 | 0.00 | 0.969 | 0.969 |
Lactose Degradation | 9 | 1 | 0.00 | 0.969 | 0.969 |