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Table 10 Metabolites correlated to serum Insulin Growth Factor Binding Protein 3 (IGFBP3) (Pearson’s correlation) for all patients, carbohydrate group, and fasting groups

From: Metabolic consequences of perioperative oral carbohydrates in breast cancer patients — an explorative study

Metabolite

R (All)

P (All)*

R (CH)

P (CH)*

R (F)

P (F)*

Isoleucine

0.424

0.001

0.414

0.040

0.351

0.039

Glycoproteins

0.410

0.001

0.224

0.282

0.478

0.004

Asparagine

0.401

0.001

0.364

0.073

0.399

0.018

Leucine

0.393

0.002

0.107

0.612

0.440

0.008

Acetone

0.383

0.003

0.298

0.148

0.397

0.018

Lysine

0.378

0.003

-0.017

0.937

0.459

0.006

N.acetylgroups

0.342

0.007

-0.241

0.247

0.484

0.003

Phenylalanine

0.322

0.012

0.114

0.586

0.314

0.066

Propylene-Glycol

0.321

0.012

0.044

0.833

0.349

0.040

Isopropyl-alcohol

0.319

0.013

-0.079

0.706

0.434

0.009

Alanine

0.310

0.016

0.100

0.635

0.413

0.014

Acetoacetate

0.243

0.062

0.036

0.866

0.192

0.268

Threonine

0.206

0.114

-0.250

0.228

0.395

0.019

Valine

0.196

0.134

0.050

0.814

0.082

0.640

Acetate

0.180

0.169

0.079

0.707

0.066

0.707

Lactate

-0.166

0.205

-0.347

0.090

0.207

0.232

pyruvate

-0.164

0.211

-0.287

0.164

0.131

0.453

Methionine

-0.158

0.228

-0.484

0.014

-0.066

0.704

Glycerol

0.137

0.296

-0.384

0.058

0.360

0.034

Proline

-0.124

0.345

-0.358

0.079

0.004

0.982

Creatine

0.103

0.435

0.175

0.401

0.051

0.773

Creatinine

0.084

0.522

-0.189

0.365

0.146

0.403

Methanol

0.079

0.549

0.288

0.162

-0.110

0.528

Glutamine

0.075

0.569

-0.176

0.399

0.123

0.481

Glucose

0.055

0.678

0.007

0.972

0.186

0.285

Citrate

0.031

0.812

-0.052

0.804

0.134

0.442

Dimethylsulfone

-0.005

0.967

-0.255

0.219

0.096

0.584

3-Hydroxybutyrate

-0.001

0.993

-0.320

0.119

0.046

0.794

  1. Abbreviations: CH Carbohydrate group, F Fasting group, P Pearson’s correlation p-value, R Pearson’s correlation R value.
  2. *Significant at p ≤ 0.01 after Benjamini-Hochberg correction for multiple testing
  3. **Significant at p ≤ 0.037 after Benjamini-Hochberg correction for multiple testing
  4. ***Significant at p ≤ 0.04 after Benjamini-Hochberg correction for multiple testing