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Table 6 Probability of dose de-escalation based on true risk of death in a given patient cohort

From: Assessment of precision irradiation in early non-small cell lung cancer and interstitial lung disease (ASPIRE-ILD): study protocol for a phase II trial

True Risk of Death in a Given Cohort Probability of De-Escalation for that Cohort
0.08 10%
0.15 28%
0.30 67%
  1. aAt risk levels higher than 30%, which are thought to be extremely unlikely, dose de-escalation probabilities rise further, and chances of de-escalation within the first few patients are very high