Skip to main content

Table 4 Univariate and multivariate COX analyses of parameters associated with OS and DFS in WCH cohort

From: Expression of FSCN1 and FOXM1 are associated with poor prognosis of adrenocortical carcinoma patients

 

Univariate analysis

Multivariate analysis

Variables

Hazard Ratio

95% CI

P Value.

Hazard Ratio

95% CI

P Value

OS

 Gender (Male)

0.93

0.45–1.91

0.833

–

–

–

 Age (≥65)

1.61

0.66–3.92

0.294

–

–

–

 Hormone secretion (Yes)

0.78

0.39–1.58

0.494

–

–

–

 Laterality (Right)

0.85

0.42–1.73

0.663

–

–

–

 Tumor Size (≥7.5)

0.71

0.35–1.41

0.322

–

–

–

 Stage (III + IV)

1.48

0.73–3.03

0.278

–

–

–

 Ki67 index (High)

2.86

1.41–5.81

0.004

2.39

1.15–4.99

0.02

 Symptoms (Yes)

3.45

1.32–9.05

0.012

2.22

0.82–5.96

0.115

 Fascin

4.69

1.81–12.19

0.002

2.86

1.06–7.7

0.038

 FoxM1

3.95

1.76–8.85

0.001

3.17

1.37–7.33

0.007

 Surgery type

0.88

0.42–1.88

0.745

   

DFS

 Gender (Male)

0.65

0.27–1.59

0.351

–

–

–

 Age (≥65)

1.12

0.33–3.8

0.859

–

–

–

 Hormone secretion (Yes)

1.48

0.65–3.36

0.350

–

–

–

 Laterality (Right)

1.38

0.61–3.11

0.439

–

–

–

 Tumor Size (≥7.5)

0.81

0.36–1.85

0.624

–

–

–

 Stage (III + IV)

3.58

1.31–9.79

0.013

2.81

1–7.95

0.051

 Ki67 index (High)

1.45

0.61–3.42

0.397

–

–

–

 Symptoms (Yes)

5.14

1.49–17.64

0.009

4.10

1.11–15.19

0.035

 Fascin

3.92

1.45–10.62

0.007

2.98

1.02–8.7

0.046

 FoxM1

3.34

1.35–8.23

0.009

2.98

1.14–7.8

0.026

 Surgery type

1.83

0.79–4.26

0.160

–

–

–