Table 1 clinicopathological characteristics of adrenocortical carcinomas in WCH cohort
Characteristics | Number (%) | FSCN1 | FOXM1 | ||||
|---|---|---|---|---|---|---|---|
| Â | Â | High | Low | p | High | Low | p |
Gender | |||||||
 Female | 33 (64.71) | 23 | 8 | 0.06 | 17 | 16 | 0.57 |
 Male | 18 (35.29) | 8 | 10 |  | 11 | 7 |  |
Age | |||||||
  < 65 | 44 (86.27) | 30 | 14 | 0.23 | 25 | 19 | 0.69 |
  ≥ 65 | 7 (13.73) | 3 | 4 |  | 3 | 4 |  |
Hormone secretion | |||||||
 No | 28 (54.90) | 17 | 11 | 0.57 | 9 | 19 | 0.001* |
 Yes | 23 (45.10) | 16 | 7 |  | 19 | 4 |  |
Laterality | |||||||
 Left | 29 (56.86) | 16 | 13 | 0.14 | 19 | 10 | 0.10 |
 Right | 22 (43.14) | 17 | 5 |  | 9 | 13 |  |
Tumor size (cm) | |||||||
  < 7.5 | 27 (52.94) | 20 | 7 | 0.16 | 15 | 12 | 1 |
  ≥ 7.5 | 24 (47.06) | 13 | 11 |  | 13 | 11 |  |
ENSAT tumor stage | |||||||
 1 | 4 (7.84) | 10 | 11 | 0.04* | 10 | 11 | 0.41 |
 2 | 17 (33.33) | ||||||
 3 | 20 (39.22) | 23 | 7 | 18 | 12 | ||
 4 | 10 (19.61) | ||||||
Ki67 index | |||||||
  < 20% | 30 (58.82) | 16 | 14 | 0.07 | 15 | 15 | 0.57 |
  ≥ 20% | 21 (41.17) | 17 | 4 |  | 13 | 8 |  |
Symptoms at diagnosis | |||||||
 No | 15 (29.41) | 7 | 8 | 0.11 | 6 | 9 | 0.22 |
 Yes | 36 (70.59) | 26 | 10 |  | 22 | 14 |  |