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Table 2 Diagnostic and clinic history of HPV infection of the population screened in the Program for HPV Screening and Early Detection of Cervical Cancer and registered in the SIDECAM

From: High risk HPV infection prevalence and associated cofactors: a population-based study in female ISSSTE beneficiaries attending the HPV screening and early detection of cervical cancer program

Characteristics

n (% of Total population screened)

HR-HPV positive n

HR-HPV Prevalence

nptrend

Patient’s symptoms

 Hemorrhage

   

0.67

  No

113,463

14,749

13

 

  Yes

2188

291

13

 

 Pruritus

   

0.36

  No

109,159

14,172

13

 

  Yes

6492

868

13

 

 Vaginal discharge

0.0001

  No

92,410

11,514

12

 

  Yes

23,241

3526

15

 

 Burning

0.02

  No

110,398

14,303

13

 

  Yes

5253

737

14

 

Signs observed by colposcopist

 Abnormal cervical neck

   

0.17

  No

110,213

14,300

13

 

  Yes

5438

740

14

 

 Ectropion

0.01

  No

113,947

14,783

13

 

  Yes

1704

257

15

 

 Cervicitis

0.0001

  No

108,564

13,948

13

 

  Yes

7087

1092

15

 

 Leucorrhoea

0.0001

  No

103,850

13,120

13

 

  Yes

11,801

1920

16

 

 Abnormal bleeding

0.01

  No

113,954

14,785

13

 

  Yes

1697

255

15

 

 Candidiasis

0.9

  No

115,257

14,988

13

 

  Yes

394

52

13

 

 Vaginosis

0.0001

  No

113,279

14,614

13

 

  Yes

2372

426

18

 

 Actinomyces

0.18

  No

115,599

15,039

13

 

  Yes

52

10

19

 

 Trichomonas

    

  No

115,621

15,031

13

0.006

 Yes

30

9

30

 

  Reason for follow-up

0.0001

  Previous positive HPV result

1979

570

29

 

  ASCUS o SICL

449

70

16

 

  Cancer control

1748

199

11

 

  No information

111,475

   

 Result of last Papanicolaou

   

0.004

  Negative for SICL or malignancy

601

91

15

 

  Negative with reactive or inflammatory alterations

10,124

1288

13

 

  Atypical squamous cells of uncertain significance-ASCUS

47

16

34

 

  SICL low grade CIN 1, condyloma ordinary dysplasia.

439

125

28

 

  SICL high grade CIN 2, condyloma atypic dysplasia.

22

13

59

 

  SICL high grade CIN 3 severe dysplasia

3

2

67

 

  SICL high grade CIN 3, squamous cell carcinoma in situ

2

2

100

 

  Invasive squamous cell carcinoma

6

1

17

 

  Atypia of endocervical glandular cells

52

6

12

 

  Adenocarcinoma In Situ

126

16

13

 

  No information

104,221

   

 Diagnosis of SICL

   

0.0001

  Negative

10,725

1379

13

 

  Positive

466

142

30

 

  No information

104,460

   
  1. The HR-HPV prevalence understood as the percentage of women with at least one high-risk HPV genotype detected by specific stratum for each evaluated characteristic
  2. Bold text denotes significant p values (p < 0.05). nptrend, Chi2 test np trend to determine proportion differences between groups with and without HR-HPV infection for categorical variables
  3. SICL: squamous intraepithelial cervical lesion. CIN: cervical intraepitelial neoplasm. ASCUS: atypical squamous cells of undetermined significance. SIDECAM: Women’s Cancer Detection System
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BMC Cancer

ISSN: 1471-2407

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