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Fig. 1 | BMC Cancer

Fig. 1

From: EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

Fig. 1

Flowchart of screening EGFR mutant LGG cases and landscape of EGFR alterations in LGG cohort. a LGG cases harboring EGFR-mutation were identified using MAF files from TCGA. 28 of 499 LGG cases were finally enrolled. All cases were verified with RNA-Seq, clinical data and SNP annotation available. Expression profiles of LGGs with EGFR mutation and corresponding wild-type control cases was analyzed using Limma in R to identify genes that were differentially expressed. b landscape of EGFR alterations in LGG cohort showed the population composition of the whole cohort

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