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Table 6 List of 20 significant ‘GeneMANIA functions’ that were obtained using miRNA-targeted genes in Pancreatic Cancer

From: Comparison of tumour and serum specific microRNA changes dissecting their role in pancreatic ductal adenocarcinoma: a meta-analysis

Sl.no

Function

FDR

Genes in network

1

protein kinase binding

4.84E-04

18

2

extracellular matrix organization

2.60E-03

17

3

angiogenesis

3.08E-03

15

4

cell cycle G2/M phase transition

3.08E-03

12

5

microtubule cytoskeleton organization

5.63E-03

14

6

nuclear division

6.74E-03

15

7

response to oxygen levels

8.77E-03

10

8

platelet-derived growth factor binding

8.79E-03

4

9

cell cycle checkpoint

1.11E-02

13

10

intrinsic apoptotic signaling pathway

1.13E-02

12

11

response to oxidative stress

1.31E-02

11

12

regulation of angiogenesis

1.40E-02

10

13

transmembrane receptor protein serine/threonine kinase signaling pathway

1.40E-02

13

14

integrin binding

1.42E-02

7

15

regulation of mitosis

3.14E-02

8

16

epithelial to mesenchymal transition

3.14E-02

7

17

regulation of release of cytochrome c from mitochondria

3.32E-02

5

18

cell chemotaxis

4.25E-02

10

19

endothelial cell proliferation

4.30E-02

7

20

Rho protein signal transduction

4.80E-02

6