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Fig. 5 | BMC Cancer

Fig. 5

From: MPPa-PDT suppresses breast tumor migration/invasion by inhibiting Akt-NF-κB-dependent MMP-9 expression via ROS

Fig. 5

MPPa-PDT inhibits metastasis in MCF-7 cells through the Akt/NF-κB signaling pathway. a The effect of NAC on the expression levels of Akt, p-Akt, p65, and p-p65 after MPPa-PDT. Quantifications of the proteins are shown. b The effect of SC79 on the expression levels of Akt, p-Akt, p65, and p-p65 after MPPa-PDT. Quantifications of the proteins are shown. c The effect of LY294002 on the expression levels of Akt, p-Akt, p65, and p-p65 after MPPa-PDT. Quantifications of the proteins are shown. d The effect of triciribine on the expression levels of Akt, p-Akt, p65, and p-p65 after MPPa-PDT. Quantifications of the proteins are shown. e The effect of NAC, SC79, LY294002 and triciribine on the F-actin cytoskeleton after MPPa-PDT (magnification, × 600). (n = 3; *P < 0.05 versus control group, **P < 0.01 versus control group)

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BMC Cancer

ISSN: 1471-2407

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