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Table 1 Main characteristics of all studies included in the meta-analysis

From: Prognostic role of pre-treatment C-reactive protein/albumin ratio in esophageal cancer: a meta-analysis

StudyCountryCase numberHigh expression (%)Pathological typeNAC (%)LocationTumor stageFollow-up (months)Cut-off valueMultivariate analysisHRs provided fromOutcomeNOS score
Ishibashi 2018 [12]Japan14375 (51.7)Multiple72 (50.3)22/56/6533/33/60/17NR0.085Yes/NoReport/SCOS/CSS7
Kunizaki 2018 [13]Japan11651 (44)SquamousNR15/31/190-II36/III-IV29Median 35.90.042Yes/NoReport/SCOS/CSS7
Otowa 2017 [14]Japan149114 (76.5)Squamous149 (100)24/73/52IIA24/IIB36/III89NR0.03YesReportOS6
Shao 2015 [24]China633140 (22.1)Squamous0 (0)33/428/172I106/IIa203/IIb92/III232Median 390.012YesReportOS7
Matsunaga 2019 [25]Japan16369 (42.3)Multiple95 (58.3)32/86/45012/I48/II45/III54/IV4NR0.0375NoSCOS7
Wei 2015 [22]China423147 (34.8)SquamousNR36/252/13541/131/81/23Median 35.70.055YesReportOS8
Xu 2015 [23]China46887 (18.6)Squamous0 (0)155/64/249I24/II181/IIIA121/IIIB+IIIC142Median 49.90.5YesReportOS9
Yu 2018 [26]China16085 (53.1)Squamous0 (0)26/104/30I160Median 71.80.023YesReportOS5
  1. NAC neoadjuvant chemotherapy, NR not report, HR hazard ratio, SC survival curve, OS overall survival, CSS cancer-specific survival, NOS Newcastle-Ottawa Quality Assessment Scale