Fig. 1
From: Baseline circulating stem-like cells predict survival in patients with metastatic breast Cancer
Panel (a) shows several cancer cells (HCT-116, an adenocarcinoma cell line) expressing CD133(red), EpCAM (green), and Hoechst (blue) as a positive control, under a fluorescence microscope. Panel (b) displays cancer cells (OECM-1, a squamous cell carcinoma line) expressing EpCAM (green) and Hoechst (blue), but not CD133(red), as a negative control for cCSCs. Panel (c) illustrates a typical cCSC expressing CD133(red), EpCAM (green), and Hoechst (blue) in the sample of one patient with cancer. Panel (d) reveals a typical CTC expressing EpCAM (green) and Hoechst
(blue). In this study, we defined cCSCs as a subpopulation of CTCs, according to the expression of CD133.