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Table 4 Multivariable Cox regression analyses predicting cancer-specific survival

From: Effect of lymph node dissection on stage-specific survival in patients with upper urinary tract urothelial carcinoma treated with nephroureterectomy

 All stageT1T2T3T4
Multivariable a
HR (95% CI)
Multivariable b
HR (95% CI)
Multivariable b
HR (95% CI)
Multivariable b
HR (95% CI)
Multivariable b
HR (95% CI)
LND status
 No LND1.00 (Ref.)1.00 (Ref.)1.00 (Ref.)1.00 (Ref.)1.00 (Ref.)
 LND0.81 (0.73–0.95)**0.84 (0.56–1.25)0.87 (0.61–1.24)0.83 (0.73–0.98)*0.64 (0.47–0.88)**
LND extent
 No LND1.00 (Ref.)1.00 (Ref.)1.00 (Ref.)1.00 (Ref.)1.00 (Ref.)
 Limited LND0.86 (0.75–0.96)*1.02 (0.65–1.59)1.02 (0.69–1.51)0.92 (0.78–1.16)0.61 (0.43–0.87)**
 Extended LND0.73 (0.61–0.88)**0.56 (0.29–1.08)0.65 (0.38–1.12)0.74 (0.58–0.95)*0.70 (0.47–0.96)*
Lymph node stage
 pN01.00 (Ref.)1.00 (Ref.)1.00 (Ref.)1.00 (Ref.)1.00 (Ref.)
 pNx1.32 (1.13–1.53)***1.29 (0.85–1.98)1.19 (0.83–1.72)1.22 (1.01–1.49)*1.97 (1.31–2.97)**
 pN1–32.49 (2.06–3.01)***3.40 (1.61–7.18)**3.35 (1.87–5.99)***2.32 (1.81–2.98)***2.55 (1.64–3.98)***
  1. *P < 0.05, **P < 0.01, ***P < 0.001. a Adjusted to age, gender, race, tumor location, laterality, tumor size, tumor stage, tumor grade, chemotherapy and year of surgery. b Adjusted to age, gender, race, tumor location, laterality, tumor size, tumor grade, chemotherapy and year of surgery. HR hazard ratio, 95% CI 95% confidence interval, LND lymph node dissection