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Fig. 3 | BMC Cancer

Fig. 3

From: Remodeling of hepatic stellate cells orchestrated the stroma-derived oxaliplatin-resistance through CCN3 paracrine in hepatocellular carcinoma

Fig. 3

High expression of CCN3 and α-SMA is the positively associated poor prognosis in HCC. The expression of CCN3 is positively correlated with α-SMA (a, A; a, b, c B). The expression of α-SMA in high CCN3 HCC group was higher than that of α-SMA in low CCN3 HCC group (b, A). The patients with high expression of CCN3/α-SMA had significantly lower OS and higher CRR than the patients with low expression of CCN3 (a, b, C). HCC patients were classified into three subgroups based on CCN3 and α-SMA expression levels, and patients with high expression of CCN3 and α-SMA had the highest CRR and lowest OS (c, C)

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