Fig. 1

Infiltration of HSC increased in the microenvironment of oxaliplatin-resistant HCC. IHC. Masson and Sirius staining revealed the increased expression of fibrous connective tissue and collagen accumulation in oxaliplatin-resistant HCC tissue (a). The migration ability of LX2 was higher in the CM of oxaliplatin-resistant HCC than in the CM of wild type HCC (b)