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Table 3 Multivariate analysis of repeated measures before and after adjuvant treatment in patients with colon and breast cancer and curative surgery for the cancer

From: Biopsychosocial and clinical characteristics in patients with resected breast and colon cancer at the beginning and end of adjuvant treatment

Scales

Colon cancer (n = 114)

Breast cancer (n = 89)

ANOVA results, F

Pre Mean (SD)

Post Mean (SD)

Pre Mean (SD)

Post Mean (SD)

Time x tumor

Time

Tumor site

Psy. distress (BSI) a

62.3 (6.4)

64.6 (6.7)

64.4 (7.4)

65.9 (6.8)

0.295

11.223**

4.691

 Anxiety

60.3 (7.1)

60.0 (7.2)

62.1 (8.3)

61.1 (7.6)

1.662

0.414

2.426

 Depression

59.4 (5.5)

60.1 (5.7)

60.5 (6.2)

60.2 (5.7)

1.246

0.248

0.845

 Somatization

59.9 (6.1)

64.4 (7.2)

61.3 (6.7)

65.9 (7.1)

0.034

80.033**

3.112

Coping with cancer (M-MAC) b

 Adaptive

64.8 (18.1)

63.2 (19.5)

66.3 (14.2)

59.6 (17.8)

4.199

11.602**

0.205

  Fighting spirit

77.2 (18.2)

72.4 (20.9)

77.7 (16.9)

71.8 (21.2)

0.160

13.826**

0.002

  Cognitive Avoidance

51.4 (26.6)

52.3 (28.1)

53.1 (25.2)

48.7 (25.3)

2.056

0.916

0.084

  Fatalism

35.8 (20.6)

63.7 (22.3)

38.7 (17.9)

58.7 (22.1)

6.039

13.707**

0.165

 Maladaptive

29.3 (18.5)

23.2 (18.2)

29.1 (19.3)

27.2 (20.3)

2.606

9.179**

0.612

  Helplessness

20.1 (19.1)

13.7 (17.5)

16.1 (17.6)

14.3 (19.5)

2.402

7.509**

0.610

  Anxious preoccupation

38.3 (22.9)

32.5 (22.5)

42.0 (26.0)

39.6 (24.7)

1.203

6.904**

3.124

Quality of life (EORTC-QLQ-C30) b

 Functional scale

83.5 (11.4)

77.9 (13.7)

82.5 (10.4)

75.5 (14.3)

0.572

49.525**

1.046

 Symptom scale

83.3 (10.3)

84.1 (13.4)

83.1 (13.4)

82.4 (11.7)

0.758

0.008

0.412

 Health Status scale

59.8 (18.1)

56.4 (19.4)

62.8 (17.1)

57.0 (20.3)

0.494

7.065**

0.710

 Quality of life scale

75.3 (11.1)

72.6 (12.1)

76.6 (10.6)

71.3 (12.6)

1.238

16.877**

0.021

  1. These analyses were age-adjusted.
  2. Abbreviations: BSI Brief Symptom Inventory, EORTC-QLQ-C30 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, M-MAC Mini-Mental Adjustment to Cancer, Pre before adjuvant treatment, Post after adjuvant treatment, Psy psychological, SD Standard Deviation
  3. *p < 0.01 (two-tailed), ** p < 0.001 (two-tailed)
  4. a T score. b Scale from 0 to 100