Skip to main content

Table 4 Hazard ratios of herpes zoster for lymphoid neoplasms according to the latters’ subtypes

From: Increased risk of lymphoid malignancy in patients with herpes zoster: a longitudinal follow-up study using a national cohort

Characteristics

Hazard ratio for lymphoid neoplasm

 

Unadjusted†

P-value*

Adjusted†‡

P-value*

Hodgkin’s disease (ICD-10 code = C81)

 Herpes zoster

3.34 (1.21–9.23)

0.020

3.23 (1.17–8.93)

0.024

 Reference

1.00

 

1.00

 

Follicular (nodular) non-Hodgkin’s lymphoma (ICD-10 code = C82)

 Herpes zoster

0.99 (0.28–3.52)

0.990

0.96 (0.27–3.41)

0.948

 Reference

1.00

 

1.00

 

Diffuse non-Hodgkin’s lymphoma (ICD-10 code = C83)

 Herpes zoster

1.61 (1.06–2.45)

0.025

1.51 (0.99–2.29)

0.055

 Reference

1.00

 

1.00

 

Peripheral and cutaneous T cell lymphomas (ICD-10 code = C84)

 Herpes zoster

1.49 (0.58–3.82)

0.402

1.42 (0.55–3.63)

0.467

 Reference

1.00

 

1.00

 

Other and unspecified types of non-Hodgkin’s lymphoma (ICD-10 code = C85)

 Herpes zoster

1.38 (0.93–2.06)

0.108

1.30 (0.88–1.94)

0.192

 Reference

1.00

 

1.00

 

Malignant immunoproliferative diseases (ICD-10 code = C88)

 Herpes zoster

1.66 (0.58–4.70)

0.343

1.51 (0.53–4.31)

0.441

 Reference

1.00

 

1.00

 

Multiple myeloma and malignant plasma cell neoplasm (ICD-10 code = C90)

 Herpes zoster

2.39 (1.47–3.89)

< 0.001

2.17 (1.33–3.54)

0.002

 Reference

1.00

 

1.00

 

Lymphoid leukemia (ICD-10 code = C91)

 Herpes zoster

1.02 (0.34–3.05)

0.975

1.01 (0.34–3.02)

0.988

 Reference

1.00

 

1.00

 
  1. * Cox proportional hazards regression model; a P-value < 0.05 indicates significance
  2. † Stratified model for age, sex, income, and region of residence
  3. ‡ Adjusted model for the CCI score
  4. CCI Charlson comorbidity index, CI confidence interval, ICD-10 International Statistical Classification of Diseases and Related Health Problems, tenth edition