Table 2 Relationship between SNPs at rs6721961 and Nrf2 expression (n = 50)

C/C at rs6721961 (n = 30)

C/A or A/A at rs6721961 (n = 20)

p value

Mutation (+) of Nrf2 (n = 5)

0

5

0.0543

No mutation of Nrf2 (n = 45)

30

15

Low in Nrf2 (n = 26)

High in Nrf2 (n = 24)

p value

Mutation (+) of Nrf2 (n = 5)

0

5

0.0184

No mutation of Nrf2 (n = 45)

26

19

Low in Nrf2 (n = 26)

High in Nrf2 (n = 24)

p value

C/C at rs6721961 (n = 30)

22

8

0.0005

C/A or A/A at rs6721961 (n = 20)

4

16

Mutation (+) of Nrf2 (n = 5)

No mutation of Nrf2 (n = 45)

p value

Mutation (+) of Keap1 (n = 11)

2

9

0.3057

No mutation of Keap12 (n = 39)

3

36

C/C at rs6721961 (n = 30)

C/A or A/A at rs6721961 (n = 20)

p value

Mutation (+) of Keap1 (n = 11)

7

4

0.7804

No mutation of Keap12 (n = 39)

23

16

Low in Nrf2 (n = 26)

High in Nrf2 (n = 24)

p value

Mutation (+) of Keap1 (n = 11)

4

7

0.3057

No mutation of Keap12 (n = 39)

22

17