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Table 3 Univariate and multivariate Cox regression analysis of clinical factors and ADC histogram parameters for predicting disease-free survival

From: Whole lesion histogram analysis of apparent diffusion coefficients on MRI predicts disease-free survival in locally advanced squamous cell cervical cancer after radical chemo-radiotherapy

ParameterUnivariate analysisP-valueMultivariate analysisP-value
Age (years)1.026 (0.987–1.066)0.194*1.004 (0.963–1.046)0.858
Grade
 Well/moderate1.0   
 Poorly2.731 (1.242–6.005)0.412  
 MTD1.004 (0.981–1.027)0.764  
FIGO stage
 IB/IIA1.0   
 IIB/III/IV1.256 (0.572–2.760)0.570  
SCC-Ag1.004 (0.982–1.027)0.716  
Median (×10−3 mm2/s)0.435 (0.037–5.075)0.507  
Max (× 10− 3 mm2/s)0.918 (0.613–1.373)0.676  
Mean (×10−3 mm2/s)0.397 (0.032–4.968)0.474  
Min (×10−3 mm2/s)0.171 (0.063–0.463)0.001#0.110 (0.023–0.538)0.006#
10% (×10−3 mm2/s)0.106 (0.006–1.933)0.130*1.803 (0.069–46.817)0.723
90% (×10−3 mm2/s)0.793 (0.287–2.193)0.655  
Kurtosis0.950 (0.821–0.099)0.489  
Skewness0.657 (0.350–1.233)0.188*0.724 (0.368–1.463)0.350
  1. *P < 0.3; #P < 0.05
  2. Hazard ratio (HR) data are reported per one-unit increase
  3. Data in parentheses are 95% confidence intervals