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Table 2 Characteristics of patients and values of ADC histogram parameters in recurrence (DFS ≤ 2 years) and non-recurrence (DFS > 2 years) groups

From: Whole lesion histogram analysis of apparent diffusion coefficients on MRI predicts disease-free survival in locally advanced squamous cell cervical cancer after radical chemo-radiotherapy

Parameter

Non-recurrence

n = 83 (80.6%)

Recurrence

n = 20 (19.4%)

P-value

Age (years)

50.4 ± 9.2

51.3 ± 11.4

0.973

Grade

 Well/moderate

48 (46.6%)

11(10.7%)

0.075

 Poor

35 (34.0%)

9(8.7%)

 

 MTD

42.9 ± 16.0

48.4 ± 13.1

0.115

FIGO stage

  

0.996

 IB/IIA

29(28.2%)

7(6.8%)

 

 IIB/III/IV

54 (52.4%)

13(12.6%)

 

SCC-Ag

9.7 ± 14.4

11.3 ± 15.2

0.957

Median (×10−3 mm2/s)

1.094 ± 1.117

0.912 ± 0.537

0.443

Max (× 10− 3 mm2/s)

2.202 ± 1.664

2.144 ± 0.328

0.352

Mean (×10−3 mm2/s)

1.056 ± 0.156

1.013 ± 0.119

0.372

Min (×10−3 mm2/s)

0.648 ± 0.570

0.356 ± 0.383

0.001*

10% (×10−3 mm2/s)

0.900 ± 0.817

0.757 ± 0.173

0.048*

90% (×10−3 mm2/s)

1.437 ± 1.470

1.305 ± 0.219

0.900

Kurtosis

5.575 ± .254

4.910 ± 2.541

0.286

Skewness

1.184 ± 0.602

0.912 ± 0.537

0.067

  1. Note: Data are presented as mean ± SD, with Wilcoxon rank-sum test. Data are presented number (percentages), with chi-square test. *P-value < 0.05