TY - JOUR AU - Calapre, L. PY - 2017 DA - 2017// TI - Circulating tumour DNA (ctDNA) as a liquid biopsy for melanoma JO - Cancer Lett VL - 404 UR - https://doi.org/10.1016/j.canlet.2017.06.030 DO - 10.1016/j.canlet.2017.06.030 ID - Calapre2017 ER - TY - JOUR AU - Wan, J. C. M. PY - 2017 DA - 2017// TI - Liquid biopsies come of age: towards implementation of circulating tumour DNA JO - Nat Rev Cancer VL - 17 UR - https://doi.org/10.1038/nrc.2017.7 DO - 10.1038/nrc.2017.7 ID - Wan2017 ER - TY - JOUR AU - Heitzer, E. AU - Ulz, P. AU - Geigl, J. B. PY - 2015 DA - 2015// TI - Circulating tumor DNA as a liquid biopsy for cancer JO - Clin Chem VL - 61 UR - https://doi.org/10.1373/clinchem.2014.222679 DO - 10.1373/clinchem.2014.222679 ID - Heitzer2015 ER - TY - JOUR AU - Canzoniero, J. V. AU - Park, B. H. PY - 2016 DA - 2016// TI - Use of cell free DNA in breast oncology JO - Biochimica et Biophysica Acta (BBA) - Reviews on Cancer VL - 1865 UR - https://doi.org/10.1016/j.bbcan.2016.03.006 DO - 10.1016/j.bbcan.2016.03.006 ID - Canzoniero2016 ER - TY - STD TI - Bettegowda, C., et al., Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci Transl Med, 2014. 6(224): p. 224ra24. ID - ref5 ER - TY - JOUR AU - Murtaza, M. PY - 2015 DA - 2015// TI - Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer JO - Nat Commun VL - 6 UR - https://doi.org/10.1038/ncomms9760 DO - 10.1038/ncomms9760 ID - Murtaza2015 ER - TY - JOUR AU - Wong, S. Q. PY - 2017 DA - 2017// TI - Circulating tumor DNA analysis and functional imaging provide complementary approaches for comprehensive disease monitoring in metastatic melanoma JO - JCO Precision Oncology VL - 1 UR - https://doi.org/10.1200/PO.16.00009 DO - 10.1200/PO.16.00009 ID - Wong2017 ER - TY - JOUR AU - Newman, A. M. PY - 2014 DA - 2014// TI - An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage JO - Nat Med VL - 20 UR - https://doi.org/10.1038/nm.3519 DO - 10.1038/nm.3519 ID - Newman2014 ER - TY - JOUR AU - Mattos-Arruda, L. PY - 2014 DA - 2014// TI - Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle JO - Ann Oncol VL - 25 UR - https://doi.org/10.1093/annonc/mdu239 DO - 10.1093/annonc/mdu239 ID - Mattos-Arruda2014 ER - TY - JOUR AU - Jamal-Hanjani, M. PY - 2016 DA - 2016// TI - Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer JO - Ann Oncol VL - 27 UR - https://doi.org/10.1093/annonc/mdw037 DO - 10.1093/annonc/mdw037 ID - Jamal-Hanjani2016 ER - TY - JOUR AU - Mattos-Arruda, L. PY - 2015 DA - 2015// TI - Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma JO - Nat Commun VL - 6 UR - https://doi.org/10.1038/ncomms9839 DO - 10.1038/ncomms9839 ID - Mattos-Arruda2015 ER - TY - JOUR AU - Dawson, S. -. J. PY - 2013 DA - 2013// TI - Analysis of circulating tumor DNA to monitor metastatic breast cancer JO - N Engl J Med VL - 368 UR - https://doi.org/10.1056/NEJMoa1213261 DO - 10.1056/NEJMoa1213261 ID - Dawson2013 ER - TY - STD TI - Forshew, T., et al., Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA. Science translational medicine, 2012. 4(136): p. 136ra68-136ra68. ID - ref13 ER - TY - JOUR AU - Tie, J. PY - 2015 DA - 2015// TI - Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer JO - Ann Oncol VL - 26 UR - https://doi.org/10.1093/annonc/mdv177 DO - 10.1093/annonc/mdv177 ID - Tie2015 ER - TY - STD TI - Garcia-Murillas, I., et al., Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer. Science translational medicine, 2015. 7(302): p. 302ra133-302ra133. ID - ref15 ER - TY - JOUR AU - Murtaza, M. PY - 2013 DA - 2013// TI - Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA JO - Nature VL - 497 UR - https://doi.org/10.1038/nature12065 DO - 10.1038/nature12065 ID - Murtaza2013 ER - TY - JOUR AU - Wang, W. AU - Song, Z. AU - Zhang, Y. PY - 2017 DA - 2017// TI - A comparison of ddPCR and ARMS for detecting EGFR T790M status in ctDNA from advanced NSCLC patients with acquired EGFR-TKI resistance JO - Cancer Med VL - 6 UR - https://doi.org/10.1002/cam4.978 DO - 10.1002/cam4.978 ID - Wang2017 ER - TY - JOUR AU - Zheng, D. PY - 2016 DA - 2016// TI - Plasma EGFR T790M ctDNA status is associated with clinical outcome in advanced NSCLC patients with acquired EGFR-TKI resistance JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep20913 DO - 10.1038/srep20913 ID - Zheng2016 ER - TY - JOUR AU - Sundaresan, T. K. PY - 2016 DA - 2016// TI - Detection of T790M, the acquired resistance EGFR mutation, by tumor biopsy versus noninvasive blood-based analyses JO - Clin Cancer Res VL - 22 UR - https://doi.org/10.1158/1078-0432.CCR-15-1031 DO - 10.1158/1078-0432.CCR-15-1031 ID - Sundaresan2016 ER - TY - JOUR AU - Emburgh, B. O. PY - 2014 DA - 2014// TI - Acquired resistance to EGFR-targeted therapies in colorectal cancer JO - Mol Oncol VL - 8 UR - https://doi.org/10.1016/j.molonc.2014.05.003 DO - 10.1016/j.molonc.2014.05.003 ID - Emburgh2014 ER - TY - JOUR AU - Gray, E. S. PY - 2015 DA - 2015// TI - Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma JO - Oncotarget VL - 6 UR - https://doi.org/10.18632/oncotarget.5788 DO - 10.18632/oncotarget.5788 ID - Gray2015 ER - TY - JOUR AU - Sanmamed, M. F. PY - 2015 DA - 2015// TI - Quantitative cell-free circulating BRAFV600E mutation analysis by use of droplet digital PCR in the follow-up of patients with melanoma being treated with BRAF inhibitors JO - Clin Chem VL - 61 UR - https://doi.org/10.1373/clinchem.2014.230235 DO - 10.1373/clinchem.2014.230235 ID - Sanmamed2015 ER - TY - JOUR AU - Girotti, M. R. PY - 2016 DA - 2016// TI - Application of sequencing, liquid biopsies, and patient-derived Xenografts for personalized medicine in melanoma JO - Cancer Discov VL - 6 UR - https://doi.org/10.1158/2159-8290.CD-15-1336 DO - 10.1158/2159-8290.CD-15-1336 ID - Girotti2016 ER - TY - JOUR AU - Gonzalez-Cao, M. PY - 2015 DA - 2015// TI - BRAF mutation analysis in circulating free tumor DNA of melanoma patients treated with BRAF inhibitors JO - Melanoma Res VL - 25 UR - https://doi.org/10.1097/CMR.0000000000000187 DO - 10.1097/CMR.0000000000000187 ID - Gonzalez-Cao2015 ER - TY - JOUR AU - Schreuer, M. PY - 2016 DA - 2016// TI - Quantitative assessment of BRAF V600 mutant circulating cell-free tumor DNA as a tool for therapeutic monitoring in metastatic melanoma patients treated with BRAF/MEK inhibitors JO - J Transl Med VL - 14 UR - https://doi.org/10.1186/s12967-016-0852-6 DO - 10.1186/s12967-016-0852-6 ID - Schreuer2016 ER - TY - STD TI - Lee J, et al. Circulating tumour DNA predicts response to anti-PD1 antibodies in metastatic melanoma. Ann Oncol. 2017;28. ID - ref26 ER - TY - STD TI - Reid AL, et al. Detection of BRAF-V600E and V600K in melanoma circulating tumour cells by droplet digital PCR. Clin Biochem. 2015;48. ID - ref27 ER - TY - STD TI - Calapre L, et al. Locus-specific concordance of genomic alterations between tissue and plasma circulating tumor DNA in metastatic melanoma. Mol Oncol. 2018. ID - ref28 ER - TY - STD TI - Bettegowda C, et al. Detection of circulating tumor DNA in early-and late-stage human malignancies. Sci Transl Med. 2014;6. ID - ref29 ER - TY - STD TI - Tie, J., et al., Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer. Sci Transl Med, 2016. 8(346): p. 346ra92. ID - ref30 ER - TY - STD TI - Le, D.T., et al., KEYNOTE-164: Pembrolizumab for patients with advanced microsatellite instability high (MSI-H) colorectal cancer. Journal of Clinical Oncology, 2018. 36(15_suppl): p. 3514–3514. ID - ref31 ER -