| Baseline | During RT | Follow-up |
---|
1st yeara | 2nd yeara | 3rd-5th yeara |
---|
12wa | 6 ma | 9 ma | 12 ma | every 4 m | every 6 m |
---|
Standard of care: |
Physical examination | x | x | x | x | x | x | x | x |
Flexible endoscopy | x | | x | x | x | x | x | x |
Toxicity | x | x | x | x | x | x | x | x |
QoL-questionnaire | x | | x | x | x | x | until 18th montha |
US-FNAC | x | | x | x | x | x | when indicated |
CT or MRIb | x | | x | when indicated |
FDG-PET | x | | when indicated |
Investigation under anesthesia | x | | when indicated |
RT planning CT | x | | | | | | | |
Extra in SUSPECT-2: |
Signed informed consent | x | | | | | | | |
Tracer injection and SPECT/CT | x | | | | | | | |
Contralateral SNP | only when contralateral drainage is visualized on SPECT/CT |
- aAfter end of radiotherapy
- bAccording to our institutional guidelines, patients with oral cavity or oropharyngeal tumor are staged by MRI, while laryngeal and hypopharyngeal tumors are staged by CT
- Abbreviations: w weeks, m months, RT radiotherapy, US-FNAC ultrasound-fine needle aspiration cytology, SNP sentinel node procedure