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Table 3 Univariate analyses for PFS and OS among 127 patients who underwent curative surgery for IHCC

From: Failure patterns after curative resection for intrahepatic cholangiocarcinoma: possible implications for postoperative radiotherapy

 

Median survival

(month)

P value

Median survival

(month)

P value

Age

  < 55 years old

10.0

 

18.6

 

  ≥ 55 years old

18.5

0.046

34.8

0.002

Sex

 Male

15.6

 

28.8

 

 Female

10.5

0.778

21.0

0.599

TMN staging

 I and II

30.2

 

45.5

 

 III and IV

7.7

< 0.001

15.7

< 0.001

T classification

 I

15.4

 

23.5

 

 II

10.4

 

40.2

 

 III

16.2

 

24.2

 

 IV

4.0

0.061

Not reached

0.948

Lymph node metastasis

 N0

21.2

 

40.2

 

 N1

6.1

< 0.001

11.5

< 0.001

Tumor differentiation

 Well

51.7

 

Not reached

 

 Moderate

15.6

 

28.8

 

 Poor

6.7

0.003

19.4

0.027

Resection Margin

 Positive

4.8

 

21.0

 

 Negative

15.6

0.020

25.2

0.304

Tumor size

  < 5 cm

19.8

 

28.8

 

  ≥ 5 cm

6.7

0.001

21.5

0.071

Hepatitis

    

  Positive

10.4

 

19.0

 

 Negative

17.6

0.005

25.2

0.079

Hypertension

 Yes

11.7

 

21.1

 

 No

15.6

0.856

43.0

0.074

Bile duct stone

 Yes

11.7

 

18.6

 

 No

15.6

0.657

30.4

0.063

Jaundice

 Yes

10.2

 

19.4

 

 No

15.4

0.406

25.2

0.386

Fever

 Yes

10.5

 

21.1

 

 No

15.4

0.737

24.8

0.920

Postoperative chemotherapy

 Yes

11.7

 

43.0

 

 No

15.6

0.939

23.5

0.170

CA-199

 Elevated

15.4

 

26.0

 

 Not elevated

11.7

0.961

28.8

0.887

CEA

 Elevated

7.7

 

15.5

 

 Not elevated

17.6

0.183

40.2

0.016