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Table 4 Hazard ratios for risk factors associated with mortality in colorectal cancer

From: Molecular subtyping improves prognostication of Stage 2 colorectal cancer

  

HR (95% CI)

P

PAge,Sex

PAll

Age (years)

60–80

2.3 (1.2,4.2)

0.0002

 

0.0002

80+

3.4 (1.7,6.5)

   

Male

 

1.4 (1.0,1.9)

0.0640

 

0.0175

Rectal

 

1.5 (1.0,2.1)

0.0511

0.1341

0.1341

Right side

 

0.9 (0.7,1.3)

0.5930

0.3881

0.7978

Lymph node involvement

1.5 (1.1,2.1)

0.0139

0.0046

0.0076

Local recurrence

 

2.2 (1.2,4.1)

0.0187

0.0120

0.0193

Post-operative metastasis

3.5 (2.4,5.0)

< 0.0001

< 0.0001

< 0.0001

TNM Stage

2

0.8 (0.5,1.3)

0.0004

0.0000

0.0015

3

1.3 (0.8,2.0)

   

4

3.0 (1.6,5.7)

   

CMS

2

1.0 (0.6,1.5)

0.0949

0.2619

0.4237

3

1.4 (0.8,2.6)

   

4

2.2 (1.1,4.5)

   

Unclassified

1.2 (0.7,2.1)

   
  1. Hazard ratio (HR) with 95% confidence interval (CI) and P-value from analysis of deviance from univariate models. PAge,Sex, P-value from analysis of deviance for Cox proportional hazards model with covariates for age and gender; PAll, P-value from analysis of deviance on Cox proportional hazards model including all covariates; TNM, tumour-node-metastasis; CMS, consensus molecular subtype