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Table 3 Sensitivity, specificity, PPV, NPV, and accuracy of serum FGF19 levels and the existing markers alone and in combination in small HCC cases

From: Serum fibroblast growth factor 19 serves as a potential novel biomarker for hepatocellular carcinoma

 Sensitivity (%)Specificity (%)PPV (%)NPV (%)Accuracy (%)
Single marker
 AFP30.496.580.774.174.9
 DCP33.395.579.373.471.1
 FGF1955.095.184.479.982.0
Double markers
 AFP and DCP53.691.777.179.275.4
 AFP and FGF1968.191.579.785.583.9
 DCP and FGF1966.791.079.384.079.1
Multiple markers
 AFP, DCP, and FGF1975.487.275.387.280.1