Fig. 7
From: MiR-155 promotes anaplastic thyroid cancer progression by directly targeting SOCS1
SOCS1 knockdown reverses the effects of miR-155. (NC: negative control). a Representative western blot showing the silencing of SOCS1 in 8305c and FRO cells after co-infection of miR-155 ASO and SOCS1-specific siRNA compared with cells transfected with miR-155 ASO independent. b Increase in the number of miR-155-silenced 8305c and FRO cells at different points in time after SOCS1 knockdown. c Typical photo (upper; zoom in 200 times) and fixed quantity discss (bottom) of transwell assays in 8305c and FRO cells transfection with miR-155 ASO have and not have SOCS1 knockdown (*P = 0.032 and P = 0.046 for 8305c and FRO cells, respectively). d Typical photo of the ratio of 8305c and FRO cells apoptosis after transfection with miR-155 ASO have and not have SOCS1 knockdown (*P = 0.037 and P = 0.021 for 8305c and FRO cells, respectively). e Caspase-3 of 8305c and FRO cells transfected with miR-155 ASO with and without SOCS1 knockdown (*P = 0.028 and P = 0.046 for 8305c and FRO cells, respectively)