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Fig. 3 | BMC Cancer

Fig. 3

From: MiR-155 promotes anaplastic thyroid cancer progression by directly targeting SOCS1

Fig. 3

Influence of increased miR-155 on 8305c and FRO cell proliferation and invasion. a 8305c and FRO cells were instantaneous transfection with miR-155 mimic or negative control (8305c: 7.90 ± 0.17 vs. 3.47 ± 0.10 [control], P < 0.001; FRO: 9.54 ± 0.25 vs. 3.81 ± 0.06 [control], P < 0.001). b Cell survival rates in MTT assay in miR-155 overexpression and control 8305c and FRO cells. The rate of increase in cell number increased in miR-155 overexpression cells was found (8305c: 13.4% ± 1.2, 25.6% ± 2.1, 31.5% ± 3.6 and 38.4% ± 4.4 at 24, 48, 72, and 96 h, respectively, P = 0.044; FRO: FRO: 17.1% ± 2.4, 24.2% ± 2.7, 38.4% ± 4.1 and 46.7% ± 5.3 at 24, 48, 72, and 96 h, separately, P = 0.041). cTypical photo (upper; zoom in 200 times) and fixed quantity discuss (bottom) of determination of Transwell mobile and aggressive attacks in mimic overexpression and negative dominate 8305c and FRO cells (8305c, P = 0.033; FRO: P = 0.048). All trials are done three times

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