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Fig. 3 | BMC Cancer

Fig. 3

From: Technical advance in targeted NGS analysis enables identification of lung cancer risk-associated low frequency TP53, PIK3CA, and BRAF mutations in airway epithelial cells

Fig. 3

Effect of VAF cut-off on TP53 mutation prevalence detected in AEC of subjects with or without cancer. Hotspot regions in TP53 exons 5, 6, and 7 were targeted. Variants were binned according to VAF lower limit and cumulative variants in cancer (solid symbol) or non-cancer subjects (open symbol) above the indicated VAF threshold were plotted

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