Fig. 3

Transcriptomic analysis between OS-DW cells and parental OS cells a) Bar graph representing distribution of transcripts in OS-DW cells in comparison to parental cells (OS). The significant differences are indicated by asterisk (*). b) The bar graph represents the up- and down-regulated, treatment-specific and control-specific transcription factors. c) Volcano plot showing the up- and down-regulated genes, in red and green colors respectively, whereas, blue indicates the significantly differentially expressed genes (FC>/< 10) with p-values ≤0.05. The key genes encircled in blue color are already reported to be involved in regulation of pathways associated with resistance