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Table 2 Associations between change in BMI status and the risk of CRC incidence, cancer-related mortality, and all-cause mortality among all participants stratified by BMI status at study entry

From: Longitudinal associations between BMI change and the risks of colorectal cancer incidence, cancer-relate and all-cause mortality among 81,388 older adults

BMI changeNo. of participantsIncident CRCCancer-related mortalityAll-cause mortality
No. of casesHR95% CIpNo. of casesHR95% CIpNo. of casesHR95% CIp
Under/normal weight at study entry
 Under/normal weight at follow-up21,749471.001631.00 5741.00
 Overweight at follow-up5781191.240.69, 2.230.46541.070.77, 1.500.671130.690.56, 0.85< 0.001
 Obesity at follow-up302051.520.61, 3.770.37121.130.63, 2.010.69
Overweight at study entry
 Under/normal weight at follow-up5244161.020.58, 1.810.943411.060.74, 1.510.762611.851.59, 2.16< 0.001
 Overweight at follow-up24,533681.001761.006031.00
 Obesity at follow-up5044130.930.49, 1.740.814360.820.56, 1.200.3151320.860.70, 1.040.12
Obesity at study entry
 Under/normal weight at follow-up32121.680.41, 7.000.47241.350.50, 3.700.555272.591.75, 3.85< 0.001
 Overweight at follow-up3658130.930.50, 1.740.812381.200.82, 1.760.3611471.371.13, 1.670.002
 Obesity at follow-up14,755631.001311.004921.00
  1. CRC: Colorectal cancer; BMI: Body mass index; HR: Hazard ratio; 95% CI: 95% confidence interval. HRs were adjusted by cox regression models for sex, age, race, education level, family annual income, marital status, physical activity level, family history of cancer, smoking status, screening arm, history of chronic diseases (i.e., hypertension, heart attack, stroke, emphysema, diabetes, arthritis, and osteoporosis), and baseline BMI value (continuous) Boldface means statistically significance