Table 1 Characteristics and methodology assessment of 8 studies included in the diagnosis meta-analysis
First author | Year | Country | Ethnicity | Case/Control | Assay type | SEN (%) | SPE(%) | TP | FP | FN | TN |
|---|---|---|---|---|---|---|---|---|---|---|---|
Feng Gao [22] | 2013 | China | Asian | 36/32 | SYBR | 72.20 | 68.70 | 26 | 8 | 10 | 22 |
Dongfang Tang (1) [23] | 2013 | China | Asian | 62/60 | TaqMan | 59.70 | 75.00 | 37 | 15 | 25 | 45 |
Dongfang Tang (2) [23] | 2013 | China | Asian | 34/32 | TaqMan | 67.60 | 65.60 | 23 | 11 | 11 | 21 |
Qing Geng (1) [24] | 2014 | China | Asian | 25/25 | SYBR | 87.00 | 87.00 | 22 | 3 | 3 | 22 |
Qing Geng (2) [24] | 2014 | China | Asian | 126/60 | SYBR | 86.00 | 84.00 | 108 | 10 | 18 | 50 |
Amal A [25]. | 2013 | Egypt | African | 65/37 | SYBR | 95.40 | 62.20 | 62 | 14 | 3 | 23 |
Carina Roth [26] | 2011 | Germany | Caucasian | 35/28 | TaqMan | 87.70 | 88.90 | 31 | 3 | 4 | 25 |
Dali Zheng [27] | 2011 | China | Asian | 74/68 | SYBR | 80.36 | 83.93 | 59 | 11 | 15 | 57 |