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Table 1 Clinicopathological features of CK7 negative breast cancers

From: Cytokeratin 7-negative and GATA binding protein 3-negative breast cancers: Clinicopathological features and prognostic significance

Nottingham gradeLow-grade (Grade 1 and 2)High-grade (Grade 3)
Ck7 expressionNegativePositiveP-valueNegativePositiveP-value
Agea (N)66 ± 4.4 (11)63.4 ± 1.2 (142)0.561562 ± 3.3 (25)61 ± 1.2 (168)0.7941
Nottingham grade     0.0457
 11 (2%)45 (98%)    
 210 (9%)97 (91%)    
 3   25 (13%)168 (87%) 
pT stage  0.8569  0.3657
 18 (7%)103 (93%) 11 (11%)87 (89%) 
 23 (9%)30 (91%) 9 (13%)63 (88%) 
 305 (100%) 2 (14%)12 (86%) 
 404 (100%) 2 (33%)4 (67%) 
pN stage  0.1377  0.7870
 08 (9%)82 (91%) 15 (15%)85 (85%) 
 1035 (100%) 5 (11%)42 (89%) 
 206 (100%) 1 (8%)12 (92%) 
 31 (20%)4 (80%) 1 (20%)4 (80%) 
 X2 (12%)15 (88%) 2 (8%)22 (92%) 
pM stage  0.0738  0.4031
 06 (6%)102 (95%) 16 (13%)106 (87%) 
 100 02 (100%) 
 x4 (17%)19 (83%) 2 (5%)37 (95%) 
Chemo/radiation therapy  0.2462  0.4921
 Yes6 (6%)98 (94%) 15 (12%)115 (88%) 
 No4 (12%)29 (88%) 7 (16%)38 (84%) 
  1. aAge and tumor size: mean ± SEM (standard error of mean)