From: Glioma SOX2 expression decreased after adjuvant therapy
Characteristics | SOX2 high expression(n = 21) | SOX2 low expression(n = 3) | p value |
---|---|---|---|
Age (year) | |||
 Mean (range) | 45(22–60) | 49(43–53) | 0.373 |
Sex | |||
 Male | 14 | 2 |  |
 Female | 7 | 1 | 1.000 |
WHO grade | |||
 III | 10 | 2 |  |
 IV | 11 | 1 | 0.546 |
IDH1 status | |||
 Wild type | 19 | 3 |  |
 Mutated | 2 | 0 | 1.000 |
Resection type | |||
 Total gross recection | 8 | 2 |  |
 Subtotal recection | 13 | 1 | 0.55 |
Adjuvant therapy after first surgery | |||
 Radiotherapy | 3 | 0 |  |
 Chemotherapy | 1 | 0 |  |
 Chemoradiotherapy | 10 | 2 |  |
 No adjuvant therapy | 7 | 1 | 0.266 |
Type of recurrence | |||
 Local recurrence | 19 | 1 |  |
 Distant recurrence | 2 | 1 | 0.343 |
Median PFS (month) | 12.7 | 5.4 | 0.083 |
Median OS (month) | 33.6 | 18.3 | < 0.001 |