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Table 2 Comparison of baseline clinical characteristics between SOX2 low expression and high expression group in primary glioma

From: Glioma SOX2 expression decreased after adjuvant therapy

Characteristics

SOX2 high expression(n = 21)

SOX2 low expression(n = 3)

p value

Age (year)

 Mean (range)

45(22–60)

49(43–53)

0.373

Sex

 Male

14

2

 

 Female

7

1

1.000

WHO grade

 III

10

2

 

 IV

11

1

0.546

IDH1 status

 Wild type

19

3

 

 Mutated

2

0

1.000

Resection type

 Total gross recection

8

2

 

 Subtotal recection

13

1

0.55

Adjuvant therapy after first surgery

 Radiotherapy

3

0

 

 Chemotherapy

1

0

 

 Chemoradiotherapy

10

2

 

 No adjuvant therapy

7

1

0.266

Type of recurrence

 Local recurrence

19

1

 

 Distant recurrence

2

1

0.343

Median PFS (month)

12.7

5.4

0.083

Median OS (month)

33.6

18.3

< 0.001