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Table 2 Comparison of baseline clinical characteristics between SOX2 low expression and high expression group in primary glioma

From: Glioma SOX2 expression decreased after adjuvant therapy

CharacteristicsSOX2 high expression(n = 21)SOX2 low expression(n = 3)p value
Age (year)
 Mean (range)45(22–60)49(43–53)0.373
Sex
 Male142 
 Female711.000
WHO grade
 III102 
 IV1110.546
IDH1 status
 Wild type193 
 Mutated201.000
Resection type
 Total gross recection82 
 Subtotal recection1310.55
Adjuvant therapy after first surgery
 Radiotherapy30 
 Chemotherapy10 
 Chemoradiotherapy102 
 No adjuvant therapy710.266
Type of recurrence
 Local recurrence191 
 Distant recurrence210.343
Median PFS (month)12.75.40.083
Median OS (month)33.618.3< 0.001