Skip to main content

Table 2 Univariate and multivariable analysis using prognostic factors in all of datasets

From: A reactive oxygen species scoring system predicts cisplatin sensitivity and prognosis in ovarian cancer patients

Cohort

Characteristics

Univariate Cox Regression

Multivariate Cox Regression

HR

95% CI

P

HR

95% CI

P

TCGA

Score

0.878

(0.849,0.908)

2.23*10−14

0.889

(0.857,0.922)

3.27*10−10

Age

1.019

(1.008,1.030)

0.001

1.018

(1.007,1.030)

0.002

Grade

 1

1

0.173

1

0.654

 2 vs 1

1.254

(0.302,5.21)

0.756

0.814

(0.191,3.459)

0.78

 3 vs 1

1.773

(0.44,7.138)

0.421

1.319

(0.325,5.358)

0.699

Others

2.304

(0.489,10.866)

0.291

1.256

(0.252,6.25)

0.781

Stage

 I-II

1

0.002

1

0.047

 III

2.374

(1.258,4.479)

0.008

2.226

(1.032,4.802)

0.041

 IV

3.219

(1.633,6.345)

0.001

2.805

(1.241,6.336)

0.013

Surgical debulking

1.293

(0.989,1.691)

0.061

1.138

(0.861,1.504)

0.362

Tothill

Score

0.929

(0.877,0.985)

0.013

0.924

(0.866,0.985)

0.015

Age

1.021

(1.000,1.042)

0.047

1.025

(1.003,1.047)

0.027

Grade

 1

1

0.467

1

0.804

 2 vs 1

1.964

(0.549,6.499)

0.269

1.269

(0.374, 4.309)

0.703

 3 vs 1

2.116

(0.660,6.791)

0.208

1.246

(0.369,4.200)

0.723

Others

0.751

(0.077,7.287)

0.805

0.47

(0.045,4.868)

0.527

Stage

 I-II

1

0.01

1

0.046

 III

4.012

(1.269,12.685)

0.018

3.319

(1.006,10.950)

0.049

 IV

6.657

(1.906,23.245)

0.003

5.118

(1.377,19.024)

0.015

Surgical debulking

0.608

(0.397,0.932)

0.022

0.688

(0.439,1.079)

0.104

TJ

Score

0.841

(0.746,0.949)

0.005

0.862

(0.750,0.990)

0.036

Age

1.048

(1.011,1.087)

0.011

1.050

(1.013,1.089)

0.008

Grade

 1

1

0.943

1

0.693

 2 vs 1

1.146

(0.363,3.622)

0.816

1.551

(0.470,5.126)

0.471

 3 vs 1

1.274

(0.496,3.272)

0.615

1.799

(0.638,5.075)

0.267

Others

1.538

(0.296,7.981)

0.608

2.400

(0.408,14.115)

0.333

Stage

 I-II

1

0.087

1

0.038

 III

3.101

(1.063,9.046)

0.038

3.986

(1.282,12.392)

0.017

 IV

3.661

(1.098,12.210)

0.035

4.956

(1.378,17.829)

0.014

Surgical debulking

0.443

(0.225,0.874)

0.019

0.617

(0.298,1.276)

0.193