Table 2 Multivariate associations between kidney transplantation and colorectal cancer (CRC) incidence among transplant recipients, overall and by age and sex
Variable | Kidney transplantation cohort | Comparison cohort | HR (95% CI) | Adjusted HR (95% CI) | ||||
|---|---|---|---|---|---|---|---|---|
No. CRC | PYs | Rate | No. CRC | PYs | Rate | |||
Overall | 135 | 36,207 | 372.9 | 889 | 382,346 | 232.5 | 1.59 (1.33–1.91) | 1.34 (1.11–1.62) |
Age group | ||||||||
< 50 | 13 | 7225 | 179.9 | 198 | 187,138 | 105.8 | 1.64 (0.93–2.90) | 2.08 (1.16–3.73) |
50–59 | 27 | 8098 | 333.4 | 202 | 79,980 | 252.6 | 1.27 (0.85–1.90) | 1.50 (0.99–2.28) |
60–69 | 45 | 10,991 | 409.4 | 244 | 67,386 | 362.1 | 1.12 (0.82–1.54) | 1.35 (0.97–1.87) |
≧70 | 50 | 9893 | 505.4 | 245 | 52,841 | 463.7 | 1.12 (0.82–1.50) | 1.23 (0.90–1.67) |
Sex | ||||||||
Female | 77 | 21,538 | 357.5 | 388 | 209,120 | 185.5 | 1.91 (1.50–2.44) | 1.48 (1.15–1.91) |
Male | 58 | 14,669 | 395.4 | 501 | 173,226 | 289.2 | 1.36 (1.04–1.78) | 1.20 (0.90–1.58) |