Red blood cell distribution width and platelet counts are independent prognostic factors and improve the predictive ability of IPI score in diffuse large B-cell lymphoma patients

Table 2 Univariate analysis of clinicopathological parameters for the prediction of OS and PFS in DLBCL patients(n = 349)

Parameter	Number	%	Overall survival			Progression-free survival
Parameter	Number	%	HR	95%CI	P value	HR	95%CI	P value
Gender(male)	191	54.73	0.951	0.610–1.484	0.825	1.044	0.744–1.465	0.804
age > 60	146	41.83	3.437	2.146–5.504	< 0.001	2.42	1.715–3.414	< 0.001
PLT≦126.5(×10⁹/L)	44	12.61	2.100	1.227–3.594	0.007	2.164	1.409–3.324	< 0.001
RDW > 14.35%	93	26.65	2.652	1.695–4.151	< 0.001	1.706	1.191–2.443	0.004
Low Hb level	187	53.58	1.817	1.148–2.876	0.011	1.479	1.047–2.089	0.027
B symptoms(present)	103	29.51	2.142	1.365–3.360	0.001	1.613	1.131–2.300	0.008
Ann Arbor stage III/IV	174	49.86	2.985	1.844–4.832	< 0.001	2.462	1.727–3.510	< 0.001
ECOG PS > 1	91	26.07	2.685	1.718–4.198	< 0.001	1.908	1.337–2.724	< 0.001
LDH > normal	146	41.83	2.159	1.381–3.375	0.001	1.844	1.312–2.590	< 0.001
Extranodal sites> 1	86	24.64	2.457	1.560–3.870	< 0.001	2.313	1.621–3.301	< 0.001
BM nvolvement	15	4.30	2.269	1.043–4.936	0.039	1.494	0.731–3.055	0.271
IPI > 2	101	28.94	4.097	2.616–6.417	< 0.001	2.727	1.932–3.849	< 0.001

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