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Fig. 1 | BMC Cancer

Fig. 1

From: Cisplatin-resistant triple-negative breast cancer subtypes: multiple mechanisms of resistance

Fig. 1

Title: Workflow to Identify Cisplatin-Related Processes in TNBC Subtypes. Legend: Summary of the strategy we used to identify cisplatin-related processes that are up and down-regulated in TNBC subtypes using the gene sets GS125959, GS257116 and GS263765. 1. Create a set of evolutionarily conserved genes that are associated with cisplatin. 2. Identify the conserved set of cisplatin-responsive genes that are differentially regulated in the TNBC subtypes. 3. Determine the GO biological processes and individual cisplatin-related processes that are enriched in the overlap set.

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