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Table 4 Changes in glucose and insulin-related characteristics in the study groups

From: Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients ─ a randomized trial

  Carbohydrate group (CH) Fasting group (F) Between groups Normal range
Admission values (A) Pre-operative Values (Pop) Difference within group (A-Pop) P-diff within group Admission values (A) Pre-operative Values (Pop) Difference within group (A-Pop) P-diff within group Difference between group CH vs. F P-diff between groups  
GLUCOSE (mmol/L)            4.0 to 6.0
 Median 5.05 4.70    5.30 5.10      
 Mean 5.37 5.22 – 0.15 0.625 5.34 5.11 – 0.23 0.009 +  0.072 0.824  
 IQR 4.88 to 5.05 4.25 to 5.50    4.80 to5.80 4.70 to 5.40      
 Range 4.40 to 10.00 3.2 to 12.1    4.20 to 6.40 3.30 to 6.90      
  95% CI 4.90 to 5.80 4.48 to 5.96 – 0.79 to 0.49   5.15 to 5.53 4.89 to 5.33 −0.39 to −0.061   −0.59 to 0.73   
INSULIN (mIE/L))            <  29.1
 Median 6.80 26.65    6.90 8.60      
 Mean 9.43 33.68 + 24.25 < 0.0001 9.14 9.09 – 0.58 0.940 +  24.31 < 0.0001  
 IQR 3.60 to 10.33 20.90 to 45.28    5.00 to 12.1 3.30 to 8.60      
 Range 2.00 to 32.50 6.00 to 86.60    2.00 to 24.80 2.00 to 22.00      
 95% CI 6.00 to 12.90 25.52 to 41.85 15.39 to 33.11   6.88 to 11.04 7.06 to 11.12 −1.58 to 1.47   15.34 to 33.27   
C-PEPTIDE (nM)            < 2.4
 Median 0.61     0.66 0.68      
 Mean 0.70 2.10 + 1.40 < 0.0001 0.75 0.76 + 0.004 0.926 +  1.39 < 0.0001  
 IQR 0.50 to 0.83 1.50 to 2.41    0.53 to 0.66 0.53 to 0.68      
 Range 0.34 to 1.91 0.71 to 5.10    0.38 to 1.92 0.40 to 1.45      
 95% CI 0.57 to 0.83 1.67 to 2.53 0.98 to 1.83   0.64 to 0.86 0.66 to 0.85 – 0.083 to 0.091   1.03 to 1.77   
IGF-1 (nM)            5 to 28
 Median 18.60 18.45    18.10 17.90      
 Mean 18.67 18.98 + 0.31 0.541 18.30 18.88 + 0.58 0.145 + 0.62 0.672  
 IQR 14.2 to 23.0 14.15 to 18.45    15.70 to 21.60 18.80 to 23.30      
 Range 8.5 to 30.6 10.20 to 33.50    8.60 to 32.80 9.80 to 32.80      
 95% CI 16.36 to 20.98 16.59 to 21.37 −0.72 to 1.35   16.34 to 20.25 16.89 to 20.86 – 0.21 to 1.36   −1.51 to 0.98   
IGFBP-3 (mg/L)            2.9 to 5.1
 Median 4.55 4.05    4.20 4.40      
 Mean 4.43 4.02 −0.42 < 0.0001 4.53 4.37 – 0.16 0.042 – 0.26 0.015  
 IQR 3.95 to 5.05 3.50 to 4.58    4.00 to 5.30 3.80      
 Range 3.00 to 5.60 2.70 to 5.20    2.80 to 6.50 2.80 to 5.60      
 95% CI 4.11 to 4.75 3.74 to 4.30 −0.56 to −0.27   4.24 to 4.83 4.11 to 4.64 −0.31 to − 0.0061   −0.46 to − 0.051