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Table 3 CT features of nodules in different size

From: Primary solid lung cancerous nodules with different sizes: computed tomography features and their variations

CT featuresGroup A
(n = 35)
Group B
(n = 60)
Group C
(n = 63)
Group D
(n = 67)
p-valueSig.
Shape
 Round9 (25.7)14 (23.3)15 (23.8)15 (22.4)0.986
 Oval16 (45.7)41 (68.3)42 (66.7)48 (71.6)0.060
 Polyonal5 (14.3)3 (5)4 (6.3)2 (3.0)0.154
 Irregular5 (14.3)2 (3.3)2 (3.2)2 (3.0)0.049A/BCD
Size (mm)8.2 ± 1.412.8 ± 1.317.7 ± 1.424.1 ± 2.7/ 
Heterogeneous density18 (51.4)15 (25)8 (12.7)3 (4.5)0.000A/BCD
Internal feature
 Calcification0 (−)0 (−)1 (1.6)1 (1.5)0.687
 Vacuole5 (14.3)5 (14.3)4 (6.4)11 (16.4)0.242
 Air bronchogram1 (2.9)1 (1.7)5 (7.9)12 (17.9)0.005A/BCD
 Cavity01 (1.7)7 (11.1)4 (6.0)0.051
Margin
 Lobulation10 (28.6)22 (36.7)36 (57.1)47 (70.1)0.000AB/CD
 Spiculation or spinous protuberance7 (20)27 (45)36 (57.1)47 (70.1)0.000A/BCD
Halo sign7 (20)15 (25)11 (17.5)12 (17.9)0.712
Tumor-lung interface
 Coarse26 (74.3)48 (80)55 (87.3)64 (95.5)0.013A/D
 Unclear6 (17.1)7 (11.7)3 (4.8)1 (1.5)0.016A/D
 Smooth3 (8.6)5 (14.3)5 (7.9)2 (3.0)0.553
Bronchial truncation0 (−)8 (13.3)10 (15.9)18 (26.9)0.005A/BCD
Vascular convergence6 (17.1)32 (53.3)43 (68.3)50 (74.6)0.000A/BCD
Beam-shaped opacity3 (8.6)15 (25)15 (23.8)26 (38.8)0.010A/BCD
Pleural retraction3 (8.6)22 (36.7)28 (44.4)34 (50.8)0.000A/BCD
Obstructive pneumonia0 (−)1 (1.67)4 (6.4)5 (7.5)//
  1. The data are expressed as n (%). Heterogeneous density indicates the density of nodules in addition to calcification, vacuole, air bronchogram, and cavity. A/BCD indicates there is significant difference between group A and B but no significant difference among groups of B, C and D. AB/CD indicates there is significant difference between group B and C but no significant difference between group A and B or group C and D. A/D indicates there is significant difference only between group A and D