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Table 3 CT features of nodules in different size

From: Primary solid lung cancerous nodules with different sizes: computed tomography features and their variations

CT features

Group A

(n = 35)

Group B

(n = 60)

Group C

(n = 63)

Group D

(n = 67)

p-value

Sig.

Shape

 Round

9 (25.7)

14 (23.3)

15 (23.8)

15 (22.4)

0.986

–

 Oval

16 (45.7)

41 (68.3)

42 (66.7)

48 (71.6)

0.060

–

 Polyonal

5 (14.3)

3 (5)

4 (6.3)

2 (3.0)

0.154

–

 Irregular

5 (14.3)

2 (3.3)

2 (3.2)

2 (3.0)

0.049

A/BCD

Size (mm)

8.2 ± 1.4

12.8 ± 1.3

17.7 ± 1.4

24.1 ± 2.7

/

 

Heterogeneous density

18 (51.4)

15 (25)

8 (12.7)

3 (4.5)

0.000

A/BCD

Internal feature

 Calcification

0 (−)

0 (−)

1 (1.6)

1 (1.5)

0.687

–

 Vacuole

5 (14.3)

5 (14.3)

4 (6.4)

11 (16.4)

0.242

–

 Air bronchogram

1 (2.9)

1 (1.7)

5 (7.9)

12 (17.9)

0.005

A/BCD

 Cavity

0

1 (1.7)

7 (11.1)

4 (6.0)

0.051

–

Margin

 Lobulation

10 (28.6)

22 (36.7)

36 (57.1)

47 (70.1)

0.000

AB/CD

 Spiculation or spinous protuberance

7 (20)

27 (45)

36 (57.1)

47 (70.1)

0.000

A/BCD

Halo sign

7 (20)

15 (25)

11 (17.5)

12 (17.9)

0.712

–

Tumor-lung interface

 Coarse

26 (74.3)

48 (80)

55 (87.3)

64 (95.5)

0.013

A/D

 Unclear

6 (17.1)

7 (11.7)

3 (4.8)

1 (1.5)

0.016

A/D

 Smooth

3 (8.6)

5 (14.3)

5 (7.9)

2 (3.0)

0.553

–

Bronchial truncation

0 (−)

8 (13.3)

10 (15.9)

18 (26.9)

0.005

A/BCD

Vascular convergence

6 (17.1)

32 (53.3)

43 (68.3)

50 (74.6)

0.000

A/BCD

Beam-shaped opacity

3 (8.6)

15 (25)

15 (23.8)

26 (38.8)

0.010

A/BCD

Pleural retraction

3 (8.6)

22 (36.7)

28 (44.4)

34 (50.8)

0.000

A/BCD

Obstructive pneumonia

0 (−)

1 (1.67)

4 (6.4)

5 (7.5)

/

/

  1. The data are expressed as n (%). Heterogeneous density indicates the density of nodules in addition to calcification, vacuole, air bronchogram, and cavity. A/BCD indicates there is significant difference between group A and B but no significant difference among groups of B, C and D. AB/CD indicates there is significant difference between group B and C but no significant difference between group A and B or group C and D. A/D indicates there is significant difference only between group A and D