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Fig. 3 | BMC Cancer

Fig. 3

From: Ex vivo tissue slice culture system to measure drug-response rates of hepatic metastatic colorectal cancer

Fig. 3

Tumor- proliferative activity (Ki-67) of treated (Cetuximab, Pembrolizumab and Oxaliplatin) and untreated (control) tissue slices. Additionally, one 1 mm2 representative section of the original tumor tissue was included in the analysis (routine-diagnostic). The percentage of Ki-67 positive tumor cells is depicted in Box-Jitter plots. Statistical differences were calculated using the Mann-Whitney U test and are marked (* p value ≤0.05; ** p value ≤0.01). a- original tumor; b- control; c- Oxaliplatin 20 μM; d- Oxaliplatin 5 μM; e- Cetuximab 200 nM; f- Cetuximab 20 nM; g- Pembrolizumab 1400 nM; h- Pembrolizumab 140 nM

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