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Table 1 Comparison of the clinicopathological parameters of the operable breast cancer patients (n = 191) according to DTC status in bone marrow before primary surgery

From: Detection of disseminated tumor cells in bone marrow predict late recurrences in operable breast cancer patients

VariableNo. of patients(n = 191)Pre-operative DTC statusP-values
Positive
(n = 30)
Negative
(n = 161)
Age (%)0.028
  < =55 years949 (10)85 (90) 
  > 55 years9721 (22)76 (78) 
Lymph node status (%)0.016
 pN013315 (11)118 (89) 
 pN1–25815 (26)43 (74) 
Tumor size (%)0.816
 pT114522 (15)123 (85) 
 pT2–4468 (17)38 (83) 
Tumor grade (%)0.421
 1678 (12)59 (88) 
 27515 (20)60 (80) 
 3467 (15)39 (85) 
 Unknown3   
Estrogen receptor status (%)0.612
 ER positive15223 (15)129 (85) 
 ER negative367 (19)29 (81) 
 Unknown3   
Progesterone receptor status (%)0.549
 PgR positive9113 (14)78 (86) 
 PgR negative9117 (19)74 (81) 
 Unknown9   
Histological type (%)0.088
 Ductal15120 (13)131 (87) 
 Lobular227 (32)15 (68) 
 Other183 (17)15 (83) 
MAI status (%)0.678
 High MAI (≥10)6011 (18)49 (82) 
 Low MAI (<  10)11919 (16)100 (84) 
Adjuvant therapy (%)0.029
 Chemotherapy214 (19)17 (81) 
 Endocrine therapy259 (36)16 (64) 
 Chemo- and endocrine therapy323 (9)29 (91) 
 No therapy11314 (12)99 (88) 
  1. p-value ≤0.05 are in bold