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Table 1 Comparison of the clinicopathological parameters of the operable breast cancer patients (n = 191) according to DTC status in bone marrow before primary surgery

From: Detection of disseminated tumor cells in bone marrow predict late recurrences in operable breast cancer patients

Variable

No. of patients(n = 191)

Pre-operative DTC status

P-values

Positive

(n = 30)

Negative

(n = 161)

Age (%)

0.028

  < =55 years

94

9 (10)

85 (90)

 

  > 55 years

97

21 (22)

76 (78)

 

Lymph node status (%)

0.016

 pN0

133

15 (11)

118 (89)

 

 pN1–2

58

15 (26)

43 (74)

 

Tumor size (%)

0.816

 pT1

145

22 (15)

123 (85)

 

 pT2–4

46

8 (17)

38 (83)

 

Tumor grade (%)

0.421

 1

67

8 (12)

59 (88)

 

 2

75

15 (20)

60 (80)

 

 3

46

7 (15)

39 (85)

 

 Unknown

3

   

Estrogen receptor status (%)

0.612

 ER positive

152

23 (15)

129 (85)

 

 ER negative

36

7 (19)

29 (81)

 

 Unknown

3

   

Progesterone receptor status (%)

0.549

 PgR positive

91

13 (14)

78 (86)

 

 PgR negative

91

17 (19)

74 (81)

 

 Unknown

9

   

Histological type (%)

0.088

 Ductal

151

20 (13)

131 (87)

 

 Lobular

22

7 (32)

15 (68)

 

 Other

18

3 (17)

15 (83)

 

MAI status (%)

0.678

 High MAI (≥10)

60

11 (18)

49 (82)

 

 Low MAI (<  10)

119

19 (16)

100 (84)

 

Adjuvant therapy (%)

0.029

 Chemotherapy

21

4 (19)

17 (81)

 

 Endocrine therapy

25

9 (36)

16 (64)

 

 Chemo- and endocrine therapy

32

3 (9)

29 (91)

 

 No therapy

113

14 (12)

99 (88)

 
  1. p-value ≤0.05 are in bold