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Table 3 HPV-positive vs. HPV-negative OPSCC

From: Low prevalence of p16-positive HPV-related head-neck cancers in Thailand: tertiary referral center experience

 

HPV+ (n = 16)

HPV- (n = 94)

p-value

 

n

%

n

%

Mean age (years)

59.1

59.0

0.98

M:F ratio

4.3:1

6.8:1

0.52

NK morphology

8

44%

0

0%

<  0.001a

K morphology

5

28%

79

86%

 

p16-positive

15

93.75%

16

17%

<  0.001a

Tonsil

13

81.25%

24

25.53%

<  0.001a

Alive

13

81.25%

29

30.85%

<  0.001a

Median survival (months)

34

15

0.03a

T1–2 stage

12

75%

34

36.17%

0.006a

N1–3 stage

13

81.25%

66

70.21%

0.55

M1 stage

0

0%

6

7%

0.26

Smoking

8/16

50%

68/85

80%

0.01a

Alcohol

8/12

67%

54/74

74%

0.73

  1. a denotes statistically significant difference
  2. HPV human papilloma virus, NK non-keratinizing, K keratinizing
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BMC Cancer

ISSN: 1471-2407

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