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Table 3 HPV-positive vs. HPV-negative OPSCC

From: Low prevalence of p16-positive HPV-related head-neck cancers in Thailand: tertiary referral center experience

  HPV+ (n = 16) HPV- (n = 94) p-value
  n % n %
Mean age (years) 59.1 59.0 0.98
M:F ratio 4.3:1 6.8:1 0.52
NK morphology 8 44% 0 0% <  0.001a
K morphology 5 28% 79 86%  
p16-positive 15 93.75% 16 17% <  0.001a
Tonsil 13 81.25% 24 25.53% <  0.001a
Alive 13 81.25% 29 30.85% <  0.001a
Median survival (months) 34 15 0.03a
T1–2 stage 12 75% 34 36.17% 0.006a
N1–3 stage 13 81.25% 66 70.21% 0.55
M1 stage 0 0% 6 7% 0.26
Smoking 8/16 50% 68/85 80% 0.01a
Alcohol 8/12 67% 54/74 74% 0.73
  1. a denotes statistically significant difference
  2. HPV human papilloma virus, NK non-keratinizing, K keratinizing