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Table 5 Univariate and multivariate analysis of the pre-TACE radiological appearances variables related to near-compete necrosis

From: Radiological appearance of hepatocellular carcinoma predicts the response to trans-arterial chemoembolization in patients undergoing liver transplantation

Variables Tumor necrosis < 90% Tumor necrosis ≥90% P value
Enhancement pattern in arterial phase
 hyperenhancement 19 35 0.002
 Hypo/isoenhancement 10 2
Heterogeneous enhancement
 Presence 17 23 0.770
 Absence 12 14
Typical enhancement
 Presence 12 27 0.010
 Absence 17 10
Intratumoral necrosis
 Presence 2 8 0.190
 Absence 27 29
Attenuation on precontrast phase
 Hypoattenuation 5 9 0.485
 isoattenuation 24 28
Tumor margin
 Smooth 16 31 0.011
 Lobulated/infiltrative 13 6
Tumor capsular
 Presence 9 13 0.726
 Absence 20 24
Radiological classification
 Type A 16 35 0.000a
 Type B/Type C 13 2
  1. aIndependently related to near-complete necrosis on the multivariate analysis (radiological classification RR = 14.2, 95% CI = 2.9–70.6, p = 0.001)