Radiological appearance of hepatocellular carcinoma predicts the response to trans-arterial chemoembolization in patients undergoing liver transplantation

Table 4 Univariate analysis of the demographic and pathological variables related to near-compete necrosis

Variables	Tumor necrosis < 90%	Tumor necrosis ≥90%	Chi-square
Sex
Male	24	24	P = 0.105
Female	5	13	P = 0.105
Age
≤ 60 years	11	19	P = 0.277
> 60 years	18	18	P = 0.277
Etiology
HCV positive	14	25	P = 0.114
HCV negative	15	12	P = 0.114
AFP
≤ 200 ng/dL	23	33	P = 0.444
> 200 ng/dL	6	4	P = 0.444
Child-Pugh class
A	18	31	P = 0.045
B	11	6	P = 0.045
Milan criteria
Within	20	19	P = 0.149
Beyond	9	18	P = 0.149
Waiting time
0–6 months	26	31	P = 0.743
> 6 months	3	6	P = 0.743
Time between first TACE and LT
< 3 months	15	20	P = 0.744
3–6 months	9	13
> 6 months	5	4
Total number of TACE by lesion
≤ 1	25	35	P = 0.456
> 1	4	2	P = 0.456
TACE procedure
DEB-TACE	13	14	P = 0.566
Lipiodol-TACE	16	23	P = 0.566
Tumor number
1	16	18	P = 0.219
2	8	6
≥ 3	5	13
Tumor diameter
≤ 3 cm	15	17	P = 0.641
> 3 cm	14	20	P = 0.641
Tumor location
right	18	22	P = 0.748
left	8	6
both	5	9
Vascular invasion
Presence	8	6	P = 0.262
Absence	21	31	P = 0.262
Tumor differentiation
Well/Mod	27	35	P = 1.000
Poor	2	2	P = 1.000

Abbreviation: HCV hepatitis C virus, AFP α-fetoprotein, TACE transarterial chemoembolisation, LT liver transplantation, DEB drug-eluting bead

ISSN: 1471-2407