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Table 3 Multiple hypothesis testing of the association of gene SPAG5 with endocrine therapy and chemotherapy

From: The prognostic association of SPAG5 gene expression in breast cancer patients with systematic therapy

 

RFS

OS

DMFS

HR

95% CI

P-value

HR

95% CI

P-value

HR

95% CI

P-value

Systemic therapy subtypes

 Endocrine therapy

1.61

1.26–2.04

< 0.001

1.95

1.47–2.60

< 0.001

1.45

0.85–2.48

ns,0.17

 Chemotherapy

1.54

1.21–1.98

< 0.001

1.57

1.16–2.12

0.0033

1.10

0.70–1.71

ns,0.68

 Endo + chemo

1.69

1.02–2.82

ns,0.0428

1.67

1.01–2.80

ns,0.051

0.99

0.34–2.86

ns,0.988

  1. ns Not significant after correction for multiple hypothesis testing, endo Endocrine therapy, chemo Chemotherapy