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Table 3 Multiple hypothesis testing of the association of gene SPAG5 with endocrine therapy and chemotherapy

From: The prognostic association of SPAG5 gene expression in breast cancer patients with systematic therapy

  RFS OS DMFS
HR 95% CI P-value HR 95% CI P-value HR 95% CI P-value
Systemic therapy subtypes
 Endocrine therapy 1.61 1.26–2.04 < 0.001 1.95 1.47–2.60 < 0.001 1.45 0.85–2.48 ns,0.17
 Chemotherapy 1.54 1.21–1.98 < 0.001 1.57 1.16–2.12 0.0033 1.10 0.70–1.71 ns,0.68
 Endo + chemo 1.69 1.02–2.82 ns,0.0428 1.67 1.01–2.80 ns,0.051 0.99 0.34–2.86 ns,0.988
  1. ns Not significant after correction for multiple hypothesis testing, endo Endocrine therapy, chemo Chemotherapy